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Organic Functional Materials: Liquid Crystals, Organic Electronics, Nanoelectronics

University of Freiburg, Institute for Physical Chemistry (HS PC), Albertstr. 23

Mar 8-10, 2017; 9:00-12:00 and 13:00-16:00

Announcement  •  Lecture Script


Applied Fluoroorganic Chemistry: Synthesis, Liquid Crystals, Pharmaceuticals

University of Freiburg, Institute for Physical Chemistry (HS PC), Albertstr. 23

Aug 2-4, 2017; 9:00-12:00 and 13:00-16:00

Announcement  •  Lecture Script

 

Recommended Reading

General Fluoroorganic Chemistry

P. Kirsch, Modern Fluoroorganic Chemistry: Synthesis, Reactivity, Applications (2nd, completely revised and enlarged ed.), Wiley-VCH, Weinheim, 2013.

T. Hiyama, Organofluorine Compounds: Chemistry and Applications, Springer, Berlin, 2007.

K. Uneyama, Organofluorine Chemistry, Blackwell, 2006.

J.-P. Begue, D. Bonnet-Delpont, Bioorganic and Medicinal Chemistry of Fluorine, Wiley & Sons, 2008.

R. D. Chambers, Organofluorine Chemistry: Fluorinated Alkenes and Reactive Intermediates in Topics in Current Chemistry, Springer, Berlin, 2007.

R. D. Chambers, Fluorine in Organic Chemistry (G. Olah; Ed.), Wiley Interscience, 1973.

M. Hudlicky, Chemistry of Organic Fluorine Compounds – A Laboratory Manual, Ellis Horwood Ltd., John Wiley & Sons, 1976.

I. C. Knunyants, G. G. Yakobson, Eds., Syntheses of Fluoroorganic Compounds, Springer Verlag, 1985.

R. E. Banks, Ed., Preparation, Properties and Industrial Applications of Organofluorine Compounds, Ellis Horwood Ltd., John Wiley & Sons, 1982.

R. E. Banks, D. W. A. Sharp, J. C. Tatlow, Eds., Fluorine – The First Hundred Years (1886-1986), Elsevier Sequoia, New York 1986.

S. T. Purrington, B. S. Kagen, Chem. Rev. 1986, 86, 997-1018.

J. Mann, Chem. Soc. Rev. 1987, 16, 381-436.

G. A. Olah, R. D. Chambers, G. K. Surya Prakash, Eds., Synthetic Fluorine Chemistry, Wiley, New York 1992.

J. A. Wilkinson, Chem. Rev. 1992, 92, 505-519.

List of reviews on fluoroorganic chemistry: G. Resnati, Tetrahedron 1993, 49, 9385.

R. E. Banks, B. E. Smart, J. C. Tatlow, Eds., Organofluorine Chemistry, Plenum Press, New York 1994.

Special issue on fluorine chemistry: Chem. Rev. 1996, 96, 1557-1823.

Atmospheric chemistry of CFC (Nobel lecture): F. S. Rowland, Angew. Chem. 1996, 108, 1908-1921.

J. M. Percy, Building Block Approaches to Aliphatic Organofluorine Compounds in Topics in Current Chemistry (R. D. Chambers; Ed.), Vol. 193, pp. 132-187, Springer, Berlin-Heidelberg, 1997.

General overview: G. Sandford, Phil. Trans. R. Soc. Lond. A, 2000, 358, 455-471.

“Fluoroproducts – the extremophiles”: K. Jones, G. Stead, J. Fluorine Chem. 2000, 104, 5-18.

Unexpected aspects of the atmospheric chemistry of perfluorinated compounds: W. T. Sturges, T. J. Wallington, M. D. Hurley, K. P. Shine, K. Sihra, A. Engel, D. E. Oram, S. A. Penkett, R. Mulvaney, C. A. M. Brenninkmeijer, Science 2000, 289, 611-613.

Terraforming of Mars using perfluorocarbons and SF6: M. F. Gerstell, J. S. Francisco, Y. L. Young, C. Boxe, E. T. Aaltonee, Proc. Nat. Acad. Sci. 2001, 98, 2154-2157.

Safe working with hydrofluoric acid and other fluorochemicals: D. Peters, R. Miethchen, J. Fluorine Chem. 1996, 79, 161-165.

Special Topics

Electrophilic fluorination: a) S. Rozen, Chem. Rev. 1996, 96, 1717-1736. b) G. S. Lal, G. P. Pez, R. G. Syvret, Chem. Rev. 1996, 96, 1737-1756.

Electrophilic perfluoroalkylation: T. Umemoto, Chem. Rev. 1996, 96, 1757-1777.

Electrochemical fluorination: a) J. H. Simons Memorial Issue, J. Fluorine Chem. 1986 (ganzes Heft). b) P. Sartori, N. Ignatiev, J. Fluorine Chem. 1998, 87, 157-162.

Fluorination with SF4, DAST und similar reagents: a) C.-L. J. Wang, Org. React. 1985, 34, 319-400. b) W. J. Middleton, J. Org. Chem. 1975, 40, 574-578.

Chemistry of highly fluorinated carbanions: W. B. Farnham, Chem. Rev. 1996, 96, 1633-1640.

Perfluoroalkylsilanes and other nucleophilic perfluoroalkylation reagents: a) G. K. S. Prakash in Synthetic Fluorine Chemistry (G. A. Olah, R. D. Chambers, G. K. S. Prakash, Eds.), John Wiley & Sons, New York, 1992, pp. 227-246. b) D. J. Burton in Synthetic Fluorine Chemistry (G. A. Olah, R. D. Chambers, G. K. S. Prakash, Eds.), John Wiley & Sons, New York, 1992, pp. 205-226.

Synthesis with fluorinated ylides: D. J. Burton, Z.-Y. Yang, W. Qiu, Chem. Rev. 1996, 96, 1641-1715.

Synthesis with amine-hydrogen fluoride complexes: G. A. Olah, X.-Y. Li in Synthetic Fluorine Chemistry (G. A. Olah, R. D. Chambers, G. K. S. Prakash, Eds.), John Wiley & Sons,New York, 1992, pp. 163-204.

Oxidative fluorodesulfuration: a) S. C. Sondej, J. A. Katzenellenbogen, J. Org. Chem. 1986, 51, 3508-3513. b) M. Kuroboshi, T. Hiyama, Synlett 1994, 251-252. c) K. Kanie, Y. Tanaka, K. Suzuki, M. Kuroboshi, T. Hiyama, Bull. Chem. Soc. Jpn. 2000, 73, 471-484.

Orthometallation: F. Mongin, R. Maggi, M. Schlosser, Chimia 1996, 50, 650-652.

Fluorinated carbenes: D. L. S. Brahms, W. P. Dailey, Chem. Rev.1996, 96, 1585-1632.

Fluorinated radicals: W. R. Dolbier, Chem. Rev. 1996, 96, 1557-1584.

Selective direct fluorination with elemental fluorine: J. Hutchinson, G. Sandford, Elemental Fluorine in Organic Chemistry in Topics in Current Chemistry (R. D. Chambers; Ed.), Vol. 193, pp. 2-38, Springer Verlag, Berlin-Heidelberg, 1997.

Stereoselective synthesis of fluoroorganic compounds: V. A. Soloshonok; Ed., Enantiocontrolled Synthesis of Fluoro-Organic Compounds – Stereochemical Challenges and Biomedicinal Targets, Wiley, Weinheim, 2000.

Fluoropharmaceuticals

R. Filler, Y. Kobayashi, L. M. Yagupolskii; Eds., Biomedicinal Aspects of Fluorine Chemistry, Elsevier,Amsterdam, 1993.

V. P. Kukhar, V. A. Soloshonok; Eds., Fluorine-Containing Amino Acids: Synthesis and Properties, Wiley, Chichester, 1994.

I. Ojima, J. R. McCarthy, J. T. Welch; Eds., Biomedical Frontiers of Fluorine Chemistry, American Chemical Society Symposium Series #639, American Chemical Society, Washington, DC, 1996.

Fluoroorganic Chemistry: Synthetic Challenges and Biomedicinal Rewards, Tetrahedron Symposia in Print No. 58, Tetrahedron 1996, 52, 1-330.

J. McCarthy, “Utility of Fluorine in Biologically Active Molecules”, Tutorial, 219th ACS National Meeting, San Francisco, USA, 2000.

Special supplement “Focus on Fluorine Chemistry”, Chimia Oggi – Chemistry Today, 2005, 23(3).

D. O'Hagan, “Fluorine in Health Care: Organofluorine Containing Blockbuster Drugs”, J. Fluorine Chem., 2010, 131, 1071-1081.

Liquid Crystals

General synthetic methodology: E. Poetsch, Kontakte (Darmstadt) 1988 (2), 15-28.

Liquid crystals for LCD: U. Finkenzeller, Spektrum der Wissenschaft 1990 (8), 55-62.

All about liquid crystals: D. Demus, J. Goodby, G. W. Gray, H.-W. Spiess, V. Vill; Eds., Handbook of Liquid Crystals, Wiley-VCH, Weinheim, 1998.

Active matrix liquid crystal displays (AM-LCD): S. Kobayashi, H. Hori, Y. Tanaka, Active Matrix Liquid Crystal Displays in Handbook of Liquid Crystal Research (P. J. Collings, J. S. Patel; Eds.), Oxford University Press, New York - Oxford, 1997, 415-444.

Liquid crystals with negative dielectric anisotropy: P. Kirsch, V. Reiffenrath, M. Bremer, Synlett 1999, 389-396.

Liquid crystals for active matrix LCD: P. Kirsch, M. Bremer, Angew. Chem. 2000, 112, 4000-4021; Angew. Chem. Int. Ed. 2000, 39, 4000-4019.

Chiral liquid crystals: G. Solladié, R. G. Zimmermann, Angew. Chem. 1984, 96, 335-349; Angew. Chem. Int. Ed. 1984, 23, 348-362.

Industrial application of chiral liquid crystals: D. Pauluth, A. E. F. Wächtler in Synthesis and Application of Chiral Liquid Crystals in Chirality in Industry, Vol. II (A. N. Collins, G. N. Sheldrake, J. Crosby; Eds.), Wiley, New York, 1997, 264-285.

 
 
 

 
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LECTURES
 
 


"Organic Functional Materials: Liquid Crystals, Organic Electronics, Nanoelectronics", University of Freiburg, Institute for Physical Chemistry (HS PC), Mar 8-10, 2017

"Applied Fluoroorganic Chemistry: Synthesis, Liquid Crystals, Pharmaceuticals", University of Freiburg, Institute for Physical Chemistry (HS PC), Aug 2-4, 2017

 

 
BOOKS
 
 

P. Kirsch
Modern Fluoroorganic Chemistry, 2nd ed.

 


J.-P. Begue, D. Bonnet-Delpont
Bioorganic and Medicinal Chemistry 
of Fluorine


 

 
 
 
 
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